Images posted by Ukraine's state emergency service showed mangled buildings and courtyards scattered with debris as rescue workers tackled a fire.
"Unfortunately, our country does not yet have a sufficient number of high-quality air defence systems to protect our entire territory and shoot down all enemy targets," Zelenskiy said in his nightly video address.
"We will do everything possible and impossible to make our air defences the strongest."
Ukraine, he said, needed to protect its own territory and "in future become the basis of a European air shield.
He said Ukrainian air defences had downed more than 3,000 targets of various types over the 16 months of war.
Persons:
Read, Volodymyr Zelenskiy, Zelenskiy, Dan Peleschuk, Timothy Heritage, Andrew Heavens, Ron Popeski
Organizations:
Press, State Emergency Service of, Ukraine, Thomson
Locations:
Ukraine, Sumy, State Emergency Service of Ukraine, KYIV, Russian, Ukrainian, Moscow, Russia